Dibyendu Maity

Computational Biophysics • Molecular Simulation • Machine Learning
S.N. Bose National Centre for Basic Sciences, Kolkata, India

Research Summary

Computational scientist specializing in nucleation kinetics, structural ordering in clathrate hydrates, and the development of machine learning tools for molecular simulations. My research integrates microsecond-scale molecular dynamics with deep learning (Variational Autoencoders, PointNet) and enhanced sampling methods (metadynamics, adaptive sampling) to decode rare-event kinetics in condensed matter. I also develop open-source tools for reaction pathway generation and ADMET property prediction.

Education

Ph.D. in Physics
S.N. Bose National Centre for Basic Sciences, Kolkata
  • Supervisor: Dr. Suman Chakrabarty
  • Thesis: Nucleation Kinetics and Structural Ordering in Clathrate Hydrates
M.Sc. in Physics
S.N. Bose National Centre for Basic Sciences, Kolkata

Publications

Total citations: 24 • h-index: 3 • Google Scholar Profile

Technical Expertise

Simulation
GROMACS, OpenMM, PLUMED (Advanced Metadynamics, Well-Tempered Metadynamics)
Machine Learning
PyTorch, Variational Autoencoders, PointNet, Graph Neural Networks, scikit-learn
Methods
Free Energy (FEP, TI, MBAR), Enhanced Sampling, Adaptive Path Sampling, Rare-event Kinetics
Programming
Python (NumPy, SciPy, MDAnalysis, pyscal), C/C++, Bash, SLURM / HPC

Research Experience

Senior Research Fellow
S.N. Bose National Centre for Basic Sciences
  • Developed IceCoder, a VAE-based framework for automated ice polymorph identification from MD trajectories (JCTC, 2025).
  • Created PathGennie, a direction-guided adaptive sampling tool for rare-event pathway generation (JCTC, 2025).
  • Investigated solvation free energy prediction using comparative ML approaches across molecular representations.
  • Co-developed MTAN-ADMET, a multi-task neural network for drug-like molecule property prediction.
  • Studied nucleation kinetics and structural ordering of methane hydrates with alcohols and osmolytes.

Honors & Awards

Senior Research Fellowship (SRF), Govt. of India
Junior Research Fellowship (JRF), Govt. of India

References

Dr. Suman Chakrabarty
Associate Professor, S.N.B.N.C.B.S.
suman.chakrabarty@snbncbs.res.in
Reference 2
Available upon request